Natural killer cells and autoimmunity

نویسندگان

  • Anthony R French
  • Wayne M Yokoyama
چکیده

Autoimmune diseases are often characterized as clinical syndromes caused by the inappropriate activation of T or B cells resulting in systemic or organ-specific damage. However, studies support a role for the innate immune system, and in particular natural killer (NK) cells, in stimulating or suppressing autoimmunity. This review focuses on recent research elucidating a potential immunoregulatory role for NK cells in modulating T and B cell-mediated autoimmunity.

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عنوان ژورنال:
  • Arthritis Research & Therapy

دوره 6  شماره 

صفحات  -

تاریخ انتشار 2004